Extracellular Vesicles (EV)
Extracellular Vesicles are classified into three types of the sizes (Small EVs, Microvesicles(100-1000nm) and Apoptotic Bodies(1000-5000nm). Especially, the small EVs(30-100nm) including exosomes, we interested in, carry marker of cells of origin and have specialized functions in physiological processes, from coagulation and intercellular signaling to waste management. Consequently, there is a growing interest in clinical applications as biomarkers and therapies alike.
In many cases, as shown above, bio molecules can be simply classified according to their size. Focused on the fact, we design the size-based separation method to purify the molecules which researchers need.
 Classification, functions, and clinical relevance of extracellular vesicles(July 2012). Pharmacological Reviews. 64 (3): 676–705.
 Urinary extracellular vesicle biomarkers in urological cancers: From discovery towards clinical implementation”(June 2018). The International Journal of Biochemistry & Cell Biology. 99: 236–256.